Effects of Maternal Stress on Human Milk Composition and Subsequent Infant Outcomes

What this Trial Is About

Mothers of preterm infants face higher emotional stress and a greater risk of postpartum depression compared to mothers of full-term infants. This increased stress can negatively affect both the mother's ability to care for her baby and the infant's health and development. The study focuses on mothers in Idaho, where preterm births are common and vitamin D deficiency risk is heightened due to limited winter sunlight exposure, which may influence postpartum mental health. The trial is evaluating whether vitamin D supplementation during lactation improves vitamin D levels and reduces stress and depression in mothers of preterm infants. Participants are randomly assigned to receive either 2,000 IU of vitamin D or a placebo. The study includes a triple-blind design and measures outcomes at baseline, 4 weeks, and 8 weeks to assess maternal stress, depression, vitamin D status, and milk composition. During the study, mothers will have their mental health, physiological stress, self-compassion, and vitamin D levels monitored through questionnaires and laboratory tests at three time points. Researchers will also analyze the immunomodulatory components in breast milk. The total participation period lasts 8 weeks, with careful follow-up to understand the effects of vitamin D supplementation on both mother and infant health.

Impact of Vitamin D Supplements on Mental Health and Milk Composition in Mothers Living in Idaho