Actively Recruiting
Mental Health and Bolsa Familia: Clinical Trial of Cash Transfer Effects on Child Brain, Behavior, and Mental Health
Led by New York State Psychiatric Institute · Updated on 2026-04-23
450
Participants Needed
2
Research Sites
30 weeks
Total Duration
On this page
Sponsors
N
New York State Psychiatric Institute
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to evaluate the effects of the Auxilio Brasil (AB) cash transfer program on child neurodevelopment and mental health in resource-limited families in Brazil. The study focuses on children aged 7 to 10 years and investigates whether increasing cash transfers can reduce childhood adversities and improve brain function and behavior related to executive functions. The trial also explores how these cash transfers affect inflammatory markers and stress hormone activity, as well as whether these effects vary by the child's sex or gender and persist after the intervention ends. Participants are families already receiving AB cash transfers. The study randomly assigns 300 families to receive either a high supplemental cash transfer of $40 per month or a low supplemental transfer of $2 per month for two years. Up to 150 siblings aged 7 to 10 may also be included. The intervention builds on Brazil's existing national program, aiming to lift families out of poverty and study the resulting effects on children's brain and behavior. Assessments occur at baseline, about 8 and 16 months, at 24 months, and approximately 6 months after the trial ends. Throughout the study, researchers will collect data using brain MRI scans, executive function tests, blood and hair samples for inflammation and cortisol levels, family environment evaluations, and questionnaires about childhood adversity and mental health symptoms. These measures will be taken multiple times to track changes over the two-year period and post-trial. The study's goal is to understand the pathways by which cash transfers might protect children's development and mental health, providing valuable information for refining social assistance programs.
CONDITIONS
Brief Title
Impacts of Cash Transfers on Child Neurodevelopment (Auxilio Brasil)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Mothers aged 23 to 45 years old
- Currently receiving Auxilio Brasil cash transfers
- Have at least two children aged 7 to 10 years at recruitment (up to four children per family)
- Able to provide consent
- Children aged 7 to 10 years old
- Children able to provide assent
You will not qualify if you...
- Mother and child do not live in the same household
- Child has major psychiatric disorders such as Autism, Schizophrenia, or Bipolar disorder
- Child has severe disability
- Child has MRI contraindications (index child only)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 24 months
Participants receive either high or low supplemental cash transfers monthly as part of the trial to assess impacts on child neurodevelopment and related outcomes.
Assessments at Baseline, 8 months, 16 months, and 24 months
Duration - 6 months post-treatment
Participants are monitored for continued effects on child neurodevelopment and wellbeing after the treatment phase ends.
1 follow-up assessment
Trial Site Locations
Total: 2 locations
1
New York State Psychiatric Institute
New York, New York, United States, 10032
Not Yet Recruiting
2
UNIFESP
São Paulo, São Paulo, Brazil, 04023
Actively Recruiting
Research Team
C
Cristiane Duarte, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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