Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07082244

Implant Phenotype Modification Via GBR and ADM

Led by University of Michigan · Updated on 2025-08-21

40

Participants Needed

1

Research Sites

65 weeks

Total Duration

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AI-Summary

What this Trial Is About

Single implant sites with bone loss can often be managed by bone grafting alone. The purpose of this study is to determine whether putting a soft tissue graft substitute over the bone graft will provide an increased benefit for improving the health, appearance, and stability of the bone and gums surrounding the implant.

CONDITIONS

Official Title

Implant Phenotype Modification Via GBR and ADM

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 63; 18 years
  • Physically healthy or mild to moderate, well-controlled disease (ASA I or II)
  • One toothless area healed for at least 3 months in the front or premolar zone of upper or lower jaw
  • Full mouth plaque and bleeding score 60; 20%
  • Thin periodontal phenotype with bucco-lingual ridge thickness > 6mm
  • Seibert class I ridge deficiency
  • Willing to sign informed consent
Not Eligible

You will not qualify if you...

  • Uncontrolled or untreated periodontal disease
  • Currently smoking cigarettes, cannabis, or electronic cigarettes
  • Taking medications affecting bone metabolism or wound healing (e.g., bisphosphonates, corticosteroids, parathyroid hormone, RANKL inhibitors)
  • Past head and neck radiation or chemotherapy within 12 months
  • Systemic diseases impacting bone metabolism or healing (osteoporosis, osteopenia, hyperparathyroidism, Paget's disease)
  • Allergy to graft materials
  • Pregnant or trying to become pregnant
  • Unwilling to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

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Research Team

D

David Dunbar, DDS

CONTACT

A

Alice Ou, RDH, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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