Actively Recruiting
Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Led by Insel Gruppe AG, University Hospital Bern · Updated on 2024-10-30
60
Participants Needed
2
Research Sites
468 weeks
Total Duration
On this page
Sponsors
I
Insel Gruppe AG, University Hospital Bern
Lead Sponsor
U
University Hospital, Zürich
Collaborating Sponsor
AI-Summary
What this Trial Is About
Myocardial infarction with non-obstructive coronary arteries (MINOCA) (i.e.\<50% stenoses) on coronary angiography) is an underappreciated clinical entity concerning 5-6% of patients with acute myocardial infarction. Approximately 50% of these patients remain without appropriate diagnosis and treatment. The MINOCA study aims at systematically assessing the frequency of underlying pathologies of MINOCA and outcomes with a multidisciplinary etiologic work-up and follow-up of 5 years including, for the first time, an implantable cardiac monitor (ICM) to assess the frequency of atrial fibrillation as underlying cause for MINOCA.
CONDITIONS
Official Title
Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Written informed consent provided
- Acute myocardial infarction type 1 as defined by the 4th universal definition
- Non-obstructive coronary arteries with less than 50% stenosis on angiography in any potential infarct-related artery
- No clinically obvious specific cause for the acute event
- Subendocardial or transmural late gadolinium enhancement consistent with ischemic cause on cardiac magnetic resonance imaging
- For ICM group: No clear underlying cause of MINOCA and higher chance of atrial fibrillation
You will not qualify if you...
- Known atrial fibrillation or atrial flutter (ICM group only)
- History of atrial fibrillation or atrial flutter ablation (ICM group only)
- Known coronary artery disease
- Previous myocardial infarction
- Previous percutaneous coronary intervention
- Previous coronary artery bypass grafting
- Contraindications to cardiac magnetic resonance imaging such as non-MR-compatible cardiac device or glomerular filtration rate below 30 ml/min
- Contraindications to implantable cardiac monitor implantation (ICM group only)
- Clear underlying cause for MINOCA before implantable cardiac monitor implantation (ICM group only)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Bern University Hospital Inselspital
Bern, Switzerland, 3010
Actively Recruiting
2
University Hospital Zurich USZ
Zurich, Switzerland, 8091
Actively Recruiting
Research Team
L
Lorenz Räber, MD, PhD
CONTACT
S
Sarah Bär, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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