Actively Recruiting
Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors
Led by Northwell Health · Updated on 2025-09-18
50
Participants Needed
1
Research Sites
413 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will enroll patients initiating Bruton Tyrosine Kinase (BTK) inhibitors without history of documented arrhythmia while on therapy using the Medtronic LINQ-2 insertable cardiac monitor (ILR). The incidence of new onset atrial fibrillation (AF) and other arrhythmia will be determined. Actions taken in response to device detected arrhythmia will be recorded.
CONDITIONS
Official Title
Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years
- Willing to sign and date the consent form
- Willing to be remotely monitored
- Starting BTK inhibitor treatment for an approved condition such as chronic lymphocytic leukemia or Waldenstrom's
- Willing to have a Medtronic cardiac monitor inserted for at least 24 hours of continuous monitoring before starting BTK inhibitor therapy
You will not qualify if you...
- Documented atrial fibrillation or ventricular arrhythmia within the past 12 months
- Stroke or transient ischemic attack within the past year
- Currently has an implanted pulse generator, defibrillator, pacemaker, or resynchronization device
- Heart surgery within the past 90 days
- Heart attack (myocardial infarction) within the past 90 days
- Currently taking anti-arrhythmic or anticoagulant medication
- Has a condition that makes participation unsafe, such as substance abuse
- Enrolled in another study that could affect the results of this study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Northwell (Northshore University/Long Island Jewish Hospitals)
New Hyde Park, New York, United States, 11040
Actively Recruiting
Research Team
E
Efstathia Mihelis
CONTACT
R
Robert S Copeland-Halperin, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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