Comparing Standard and Tailored Training for Anal Cancer Screening and Treatment of High-Grade Intraepithelial Lesions in Nigeria

What this Trial Is About

This research aims to evaluate two training protocols designed to improve a physicians ability to screen and treat high-grade intraepithelial lesions HSILs to prevent anal cancer. The study focuses on comparing the current standard training developed in high-income countries with a new training tailored specifically for the Nigerian healthcare setting. The goal is to determine if the tailored training leads to better performance in anal cancer screening and treatment within an HIV care context. The study will first apply the standard training for 12 months to observe baseline screening and treatment practices. Then, an enhanced training called e-STH, developed through an iterative process based on local barriers and facilitators, will be implemented over 6 months. Following this, a 12-month period will evaluate the impact of the enhanced training on HSIL detection and treatment. Finally, a 6-month phase will assess the sustainability of the improved screening and treatment practices with minimal involvement from the research team. Participants involved are a single physician undergoing these training protocols at one clinic. Researchers will monitor the proportion of HSIL cases detected and treated, as well as secondary outcomes related to reach, efficacy, implementation, and sustainability of the screening program. The study uses a non-randomized, sequential design to evaluate these outcomes over a total period of 36 months, with ongoing assessments throughout each phase.

Implementation of Anal Cancer Screening and Treatment in Nigeria