Actively Recruiting
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
Led by University of Colorado, Denver · Updated on 2025-09-29
3250
Participants Needed
3
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Colorado, Denver
Lead Sponsor
U
University of Colorado Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients undergoing total knee replacement often face significant loss of strength in the quadriceps muscle, leading to ongoing weakness and reduced function over time. This research focuses on studying neuromuscular electrical stimulation (NMES), a technique that may help reduce muscle weakness after surgery. The trial aims to evaluate how effective and feasible it is to implement NMES in real-world rehabilitation settings across two large healthcare organizations. The study compares two groups of patients recovering from total knee arthroplasty (TKA). One group receives standard rehabilitation care combined with NMES using a special portable device that helps stimulate muscle contractions and tracks treatment adherence. The other group receives usual rehabilitation care without NMES. This approach allows researchers to see if adding NMES improves recovery compared to typical care alone. Participants attend outpatient physical therapy clinics and are assessed before surgery and at several points after surgery, up to 24 weeks. The study measures physical function using tests like the Timed Up and Go, sit-to-stand, quadriceps strength, knee motion, and patient satisfaction. Researchers also monitor how well NMES is used and its impact on recovery. The total participation includes regular clinic visits and outcome assessments to track progress.
CONDITIONS
Brief Title
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Outpatient physical therapy clinic is part of UCHealth or Intermountain Health
- Patient underwent primary unilateral total knee arthroplasty
- Patient attended outpatient rehabilitation at a participating clinic within 5 days after surgery
- Patient attended at least 3 total outpatient physical therapy visits
You will not qualify if you...
- Patient has implanted cardiovascular cardioverter defibrillator (ICD), active cancer, or post-operative diagnosed deep vein thrombosis in the involved lower extremity
- Patient had previous lower extremity arthroplasty less than 12 weeks before scheduled knee surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 24 weeks
Participants receive neuromuscular electrical stimulation (NMES) plus usual care rehabilitation or usual care rehabilitation alone after total knee arthroplasty to improve physical function during outpatient physical therapy.
Outpatient physical therapy visits beginning within 5 days after surgery and continuing for at least 3 visits, with assessments at baseline, 2 weeks, 4 weeks, 6 weeks, and up to 24 weeks
Trial Site Locations
Total: 3 locations
1
UCHealth
Aurora, Colorado, United States, 80045
Actively Recruiting
2
University of Colorado Denver, Anschutz
Aurora, Colorado, United States, 80045
Actively Recruiting
3
Intermountain Health
Murray, Utah, United States, 84107
Actively Recruiting
Research Team
M
Maggie Givan, MA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here