Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06906640

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Led by Duke University · Updated on 2026-04-08

420

Participants Needed

6

Research Sites

74 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

B

Bayer

Collaborating Sponsor

AI-Summary

What this Trial Is About

IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.

CONDITIONS

Official Title

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults with type 2 diabetes (T2D)
  • Receiving primary care within the healthcare system with a visit in the last 24 months (any PCP provider, including APP)
  • Evidence of chronic kidney disease (CKD) based on lab tests within the past 2 years, confirmed if not checked within 3 months: UACR >300 mg/g, or eGFR <45 ml/min/1.73 m2, or UACR 630 mg/g with eGFR <60 ml/min/1.73 m2
  • Receiving less than 100% guideline-directed medical therapy (GDMT) at baseline, including specified therapies unless contraindicated
Not Eligible

You will not qualify if you...

  • Type 1 diabetes
  • Most recent eGFR less than 20 ml/min/1.73 m2
  • Prior kidney transplant
  • Autosomal dominant polycystic kidney disease (ADPKD)
  • Active pregnancy or plans for conception within 1 year

AI-Screening

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Trial Site Locations

Total: 6 locations

1

University of Alabama

Birmingham, Alabama, United States, 35233

Actively Recruiting

2

Orlando Health

St. Petersburg, Florida, United States, 33701

Actively Recruiting

3

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

4

Essentia Institute of Rural Health

Duluth, Minnesota, United States, 55805

Actively Recruiting

5

Duke University

Durham, North Carolina, United States, 27707

Actively Recruiting

6

Baylor Scott & White

Temple, Texas, United States, 76508

Actively Recruiting

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Research Team

G

Gretchen Sanders, MSN

CONTACT

M

Monica Leyva, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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