Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT07059637

Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD

Led by The Cleveland Clinic · Updated on 2025-10-30

80

Participants Needed

1

Research Sites

111 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Sarcopenia, or skeletal muscle loss, impacts up to 40% of COPD patients and is a major cause for morbidity and mortality. Despite the high clinical significance of sarcopenia in COPD, the diagnosis remains elusive because accurate measures of skeletal muscle are not tested during routine clinical care. The goal is to use evidence-based strategies to diagnose and treat sarcopenia due to COPD. The multidisciplinary team includes a pulmonologist, pharmacist, COPD nurse, and COPD coordinator. The investigators anticipate that the approach will improve clinical outcomes for COPD patients with sarcopenia as compared to standard of care visits in ambulatory COPD clinics. The investigators will determine if the approach improves skeletal muscle mass and function, and also improves clinical outcomes related to frequency of hospitalization or ED (Emergency Department) visits, COPD exacerbations, and mortality.

CONDITIONS

Official Title

Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • COPD exacerbation was the main reason for your hospital stay or a secondary diagnosis with acute respiratory failure as the main diagnosis
  • You had a CT scan during your hospital stay showing low muscle mass in the chest area
  • You are older than 40 years
  • You have COPD confirmed by lung function tests with at least moderate airway obstruction
  • You have smoked at least 10 pack years and may be a current or former smoker
Not Eligible

You will not qualify if you...

  • You have other lung diseases such as interstitial lung disease or asthma
  • You are currently being evaluated for or listed for a lung transplant
  • You have an active cancer
  • You have serious end organ failure such as heart failure with low ejection fraction, end stage kidney disease needing dialysis, or liver cirrhosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

A

Amy Attaway, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD | DecenTrialz