Actively Recruiting

Phase Not Applicable
Age: 25Years +
FEMALE
Healthy Volunteers
NCT07225530

Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)

Led by Columbia University · Updated on 2026-02-25

600

Participants Needed

1

Research Sites

192 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to conduct a randomized controlled trial to evaluate the effectiveness of same-day HPV-based screen and treat among women living with HIV (WLH) in La Romana, Dominican Republic. With cervical cancer being a leading cause of cancer-related deaths in women living with HIV, and cervical cancer deaths being preventable through screening and early detection, this project seeks to identify factors associated with the successful implementation of the Screen, Triage, and Treat approach to inform future implementation and scale-up.

CONDITIONS

Official Title

Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR)

Who Can Participate

Age: 25Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 25 years of age
  • Female sex assigned at birth (any gender identity)
  • HIV-positive
  • Women who had cervical cancer precursor lesions removed more than 6 months ago
  • Understand Spanish
Not Eligible

You will not qualify if you...

  • Age outside the specified inclusion criteria
  • Pregnant, less than 6 weeks postpartum, or pregnancy cannot be excluded
  • History of Loop Electrosurgical Excision Procedure (LEEP) in the last 6 months
  • History of hysterectomy
  • Previous diagnosis of gynecological cancer
  • History of cancer of the anogenital tract
  • Unable or unwilling to provide informed consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

Clínica de Familia La Romana

La Romana, Dominican Republic

Actively Recruiting

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Research Team

R

Rebecca Schnall, PhD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

2

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