Methamphetamine- and trauma-induced brain injuries: comparative cellular and molecular neurobiological substrates.
Mark S Gold, Firas H Kobeissy, Kevin K W Wang...
https://pubmed.ncbi.nlm.nih.gov/19345341Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID06532370
Implementing a Contingency Management Program Addressing Methamphetamine Use For and With the People of Hawaii
Led by Queen's Medical Center · Updated on 2026-03-31
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
Q
Queen's Medical Center
Lead Sponsor
N
National Institute of General Medical Sciences (NIGMS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying contingency management (CM) as a behavioral approach to address methamphetamine use among individuals in Hawaii who have been hospitalized due to traumatic injury. The study aims to gather data on the effectiveness of a pilot CM program and to understand participant perspectives on engaging with this intervention at a Level 1 Trauma Center. This research focuses on both patient-reported and biologically-confirmed outcomes over the medium term. Participants will attend follow-up clinics up to three times per week for up to 12 weeks after discharge to complete urinalysis tests. Those who test negative for methamphetamine receive positive reinforcement through a prize draw with various rewards ranging from praise to valuable items. The program includes Treatment Effectiveness Assessments at 6 and 12 weeks, along with a qualitative interview conducted at the end of the CM program. Throughout the study, participants will provide urine samples multiple times weekly and complete scheduled assessments to measure treatment effectiveness. The primary outcomes include the Treatment Effectiveness Assessment results at 6 and 12 weeks, and qualitative feedback is collected at the program’s conclusion. The total participation period covers enrollment through 12 weeks post-discharge, with ongoing encouragement to continue engagement regardless of test results.
CONDITIONS
Brief Title
Implementing a Contingency Management Program Addressing Methamphetamine Use For and With the People of Hawaii
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Admitted trauma patients
- Age greater than 18 years old
- Urine drug screen positive for methamphetamines during the current hospitalization
- Report at least weekly methamphetamine use
- First methamphetamine use greater than 6 months prior to injury
- Report at least 4 DSM-V Amphetamine-Type Substance Use Disorder symptoms (at least moderate disease)
- Glasgow Coma Scale �3 upon arrival to the emergency department
- Ability to understand and participate in study procedures
- Ability to communicate in English
You will not qualify if you...
- Active psychosis (reporting auditory or visual hallucinations)
- Under ongoing cardiorespiratory monitoring
- Evidence of moderate or severe traumatic brain injury
- Patients who are known to be pregnant
- Prisoner
- Individuals incarcerated at the time of their hospitalization
- Individuals lacking capacity to provide, or are otherwise unable or unwilling to provide written informed consent
AI-Screening
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Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Outpatient Treatment
Duration - Up to 12 weeks
Participants complete Contingency Management sessions three times per week for up to 12 weeks, receiving incentives for methamphetamine-negative samples and encouragement to continue participation if positive.
Three visits per week for up to 12 weeks
Trial Site Locations
Total: 1 location
1
The Queen's Medical Center
Honolulu, Hawaii, United States, 90813
Actively Recruiting
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Research Team
N
Nicholas R Schumann, Clinical Psychologist
K
Karen Ng, RN
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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Published Research Related To This Trial
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Mohamad El Moheb, Juan P Herrera-Escobar, Kerry Breen...
https://pubmed.ncbi.nlm.nih.gov/33264267Treatment of stimulant use disorder: A systematic review of reviews.
Claire Ronsley, Seonaid Nolan, Rod Knight...
https://pubmed.ncbi.nlm.nih.gov/32555667Measuring recovery in opioid use disorder: clinical utility and psychometric properties of the Treatment Effectiveness Assessment.
Walter Ling, Vijay R Nadipelli, Caitlyn T Solem...
https://pubmed.ncbi.nlm.nih.gov/31239805