Actively Recruiting

Phase Not Applicable
Age: 18Months - 5Years
All Genders
Healthy Volunteers
ID07236905

Improving HIV Testing Among Children Under Five in Rural Uganda

Led by University of California, San Francisco · Updated on 2026-03-11

400

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating if HIV screening can be effectively conducted for children aged 18 months to 5 years by traditional healers in Southwestern Uganda. The study aims to determine whether caretakers accept HIV testing offered by traditional healers compared to acceptance and follow-through after referral to nearby health centers. The investigation also explores how factors like HIV-related stigma and caregiver knowledge influence testing decisions. The study involves training five traditional healers to provide pediatric-specific HIV counseling and rapid oral swab testing, while another five healers offer enhanced standard care by referring children to health facilities after education about community HIV resources. A total of 400 children will be enrolled over nine months, with half receiving testing through the healers and half referred for testing. Caregivers will complete health histories, surveys on HIV knowledge and stigma, and be offered rapid HIV testing or referral depending on the group. Participants' caregivers will be contacted monthly for three months to track follow-up testing, confirmatory testing, and treatment initiation if HIV positive. The study includes thorough monitoring of counseling and testing quality, collection of demographic and behavioral data, and exit interviews with traditional healers and caregivers to assess acceptability and sustainability. The main outcome measured is the number of children completing HIV testing within three months of enrollment.

CONDITIONS

Brief Title

Improving Access to HIV Testing for Children in Uganda

Who Can Participate

Age: 18Months - 5Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 months to 5 years old
  • Have a parent or caregiver present who can provide informed consent
  • Not previously tested for HIV in the past three months
  • Not previously known to be HIV-infected
Not Eligible

You will not qualify if you...

  • Unwilling or unable to participate in study procedures or provide written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit (in-person)

Surveillance

Duration - 3 months

Participants are monitored through monthly phone calls to check on subsequent HIV testing, confirmation of initial results if HIV reactive, and linkage to care and treatment initiation for those confirmed HIV positive.

Monthly phone calls for 3 months

Trial Site Locations

Total: 1 location

1

Mbarara University of Science and Technology

Mbarara, Uganda

Actively Recruiting

Loading map...

Research Team

A

Anneka Hooft, MD, MPH

E

Elizabeth Butrick, MS

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

2

Similar Trials

A Randomized, Double-Blind, Placebo-Controlled Trial of Resm...

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

Actively Recruiting

10 locations

Adaptation and Implementation of an Evidence-based Approach ...

HIV (Human Immunodeficiency Virus)

Actively Recruiting

1 location

Role of Empagliflozin in Metabolic Changes Associated With A...

Metabolic Syndrome

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here