Actively Recruiting
Improving HIV Testing Among Children Under Five in Rural Uganda
Led by University of California, San Francisco · Updated on 2026-03-11
400
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating if HIV screening can be effectively conducted for children aged 18 months to 5 years by traditional healers in Southwestern Uganda. The study aims to determine whether caretakers accept HIV testing offered by traditional healers compared to acceptance and follow-through after referral to nearby health centers. The investigation also explores how factors like HIV-related stigma and caregiver knowledge influence testing decisions. The study involves training five traditional healers to provide pediatric-specific HIV counseling and rapid oral swab testing, while another five healers offer enhanced standard care by referring children to health facilities after education about community HIV resources. A total of 400 children will be enrolled over nine months, with half receiving testing through the healers and half referred for testing. Caregivers will complete health histories, surveys on HIV knowledge and stigma, and be offered rapid HIV testing or referral depending on the group. Participants' caregivers will be contacted monthly for three months to track follow-up testing, confirmatory testing, and treatment initiation if HIV positive. The study includes thorough monitoring of counseling and testing quality, collection of demographic and behavioral data, and exit interviews with traditional healers and caregivers to assess acceptability and sustainability. The main outcome measured is the number of children completing HIV testing within three months of enrollment.
CONDITIONS
Brief Title
Improving Access to HIV Testing for Children in Uganda
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 months to 5 years old
- Have a parent or caregiver present who can provide informed consent
- Not previously tested for HIV in the past three months
- Not previously known to be HIV-infected
You will not qualify if you...
- Unwilling or unable to participate in study procedures or provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - 3 months
Participants are monitored through monthly phone calls to check on subsequent HIV testing, confirmation of initial results if HIV reactive, and linkage to care and treatment initiation for those confirmed HIV positive.
Monthly phone calls for 3 months
Trial Site Locations
Total: 1 location
1
Mbarara University of Science and Technology
Mbarara, Uganda
Actively Recruiting
Research Team
A
Anneka Hooft, MD, MPH
E
Elizabeth Butrick, MS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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