Actively Recruiting
Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome
Led by Nanjing First Hospital, Nanjing Medical University · Updated on 2026-04-15
180
Participants Needed
2
Research Sites
205 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
sICASBLM is a prospective controlled trial, to asses the impact of improving blood lipid management on clinical outcome of moderate to severe symptomatic intracranial atherosclerotic stenosis patients (LDL-C\>1.8mmol/L) without endovascular therapy.
CONDITIONS
Official Title
Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Moderate to severe symptomatic intracranial atherosclerotic stenosis without prior intravenous thrombolysis, thrombectomy, stent implantation, or other intravascular treatment
- Low density lipoprotein cholesterol (LDL-C) level greater than 1.8 mmol/L (70 mg/dl)
- Able to receive 3T magnetic resonance angiography or multi-mode magnetic resonance imaging with high resolution suitable for analysis
- Indications for lipid-lowering treatment with statins
- Signed informed consent approved by the study
You will not qualify if you...
- Contraindications to statin treatment
- Contraindications to or inability to undergo MRI examination
- Stenosis caused by vasculitis, arterial dissection, or moyamoya disease
- Active bleeding or significant bleeding tendency
- Severe heart, lung, or renal failure, malignant tumors or other serious diseases with high risk of death within 7 days; pregnancy or breastfeeding
- Uncontrolled severe diabetes or hypertension
- Other conditions deemed inappropriate for inclusion by investigators
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Nanjing First Hospital, Nanjing Medical University
Nanjing, Jiangsu, China, 210006
Actively Recruiting
2
Nanjing First Hospital
Nanjing, Jiangsu, China, 210006
Actively Recruiting
Research Team
J
Junshan Zhou
CONTACT
Q
Qiwen Deng
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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