Actively Recruiting
Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy
Led by Dana-Farber Cancer Institute · Updated on 2026-01-22
30
Participants Needed
1
Research Sites
298 weeks
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
A
American Institute for Cancer Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to determine whether a 16-week high intensity interval training (HIIT) exercise program will improve brain health among women undergoing chemotherapy and also improve cardiovascular (heart) function. The names of the study interventions involved in this study are/is: * High-Intensity Interval Training (HIIT)
CONDITIONS
Official Title
Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women newly diagnosed with Stage I-III breast cancer
- Age 18 years or older
- Willing and able to provide written informed consent
- Receiving neoadjuvant or adjuvant chemotherapy
- Speak English
- Able to obtain physician clearance to participate in exercise
- Able to start a supervised exercise program without cardiovascular, respiratory, musculoskeletal, or joint problems that limit moderate activity
- Have not lost 10% or more of body weight in the past 6 months
- Currently do less than 60 minutes of structured exercise per week
- Do not smoke and have not smoked in the past 12 months
- Willing to travel to Dana-Farber Cancer Institute for assessments
- Women of child-bearing potential must agree to pregnancy testing and use adequate contraception during the study and for 6 months after
You will not qualify if you...
- Uncontrolled illnesses such as active infection, uncontrolled diabetes, hypertension, or thyroid disease
- Other active cancers
- Metastatic breast cancer
- History of coronary heart or artery disease, congestive heart failure, or heart insufficiency
- Participate in more than 60 minutes of structured exercise per week
- Orthopedic or other restrictions preventing high-intensity cycling exercise
- Have a pacemaker or implantable device that is not safe for MRI
- Unable to travel to Dana-Farber Cancer Institute
- Pregnant women
- Claustrophobia
- Unable to comply with safety monitoring requirements as judged by the investigator
AI-Screening
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Trial Site Locations
Total: 1 location
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
C
Christina Dieli-Conwright, MD
CONTACT
M
Mary Norris, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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