Actively Recruiting

Age: 2Months - 25Years
All Genders
NCT06635291

Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE)

Led by IRCCS Eugenio Medea · Updated on 2024-12-16

113

Participants Needed

1

Research Sites

136 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The present study aims to investigate the clinical evolution of children with severe ABI and DoC both by using the traditional behavioral scales, namely the CRS-R, CRS-P and CNCS, and by trying to establish whether it is possible to identify any clinical markers of Emergency (E-Markers). E-Markers are behaviors that indicate a content of consciousness irrespective of the processes investigated by behavioral scales, thus they could be combined with the items of these scales to improve the diagnosis. A particular focus will be given to the identification of specific E-Markers for children aged less than 12 months, for which the CRS-P scale cannot be used. In this case, the E-markers will be compared with the specific developmental stages of newborns, giving great importance to motor abilities.

CONDITIONS

Official Title

Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE)

Who Can Participate

Age: 2Months - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suffering from an acquired brain injury due to traumatic brain injury, hypoxic events/anoxia, cerebral infections, or cerebrovascular accident
  • Age between 2 months and 25.11 years
  • Glasgow Coma Scale score of 8 or less at injury or onset
  • In vegetative state or minimally conscious state at admission
  • In subacute or chronic phase after injury
Not Eligible

You will not qualify if you...

  • Acquired brain injury caused by brain tumor
  • Acquired brain injury caused by neurodegenerative disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Scientific Institute, IRCCS E. Medea

Bosisio Parini, Lecco, Italy, 23842

Actively Recruiting

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Research Team

S

Sandra Strazzer, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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