Actively Recruiting
Development and Evaluation of a Multi-Component Intervention to Support HIV Care Engagement Among Patients Receiving Cancer Treatment in Zimbabwe
Led by Fred Hutchinson Cancer Center · Updated on 2026-05-01
300
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
Sponsors
F
Fred Hutchinson Cancer Center
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
People in Zimbabwe who have both cancer and HIV often face challenges staying connected to their HIV care while undergoing cancer treatment. This is mainly because HIV and cancer treatments are provided at different health facilities, creating barriers to care. The goal of this research is to understand these barriers and develop ways to support patients in continuing their HIV care throughout their cancer treatment. Researchers will observe two groups of people with cancer and HIV to study these challenges and improvements. The study involves two main groups. The first group will receive standard care, and their experiences with HIV care barriers during cancer treatment will be documented. Based on these findings, researchers will develop and implement strategies at Parirenyatwa Hospital's Radiotherapy Centre to improve HIV care engagement. These strategies may include better documentation, improved referral and prescription processes, and enhanced communication between cancer and HIV care teams. After these changes, a second group of patients starting cancer treatment will be observed to assess the impact and acceptability of the new strategies. Participants will be monitored over six months or until completion of their cancer treatment. Researchers will evaluate how acceptable the new strategies are to patients and staff and track missed HIV clinical visits, antiretroviral therapy (ART) adherence, and missed ART prescription refills. This detailed observation will help determine if the new health system changes support patients in maintaining their HIV care during cancer treatment.
CONDITIONS
Brief Title
Improving Engagement in HIV and Cancer Care in Zimbabwe
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Registered patient at Parirenyatwa Hospital Radiotherapy Centre, receiving cancer treatment for a new diagnosis
- HIV-positive
You will not qualify if you...
- Benign diagnosis or cancer recurrence
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 6 months or until completion of cancer treatment
Participants in the pre-intervention cohort are observed to document barriers to HIV care during cancer treatment without any new intervention.
Monthly visits for up to 6 months
Duration - Period of process improvement between cohorts
Strategies to improve HIV care engagement are developed and implemented at the Radiotherapy Centre to support better HIV care during cancer treatment.
No participant visits during this stage
Duration - Up to 6 months or until completion of cancer treatment
Participants in the post-intervention cohort receive the updated health system interventions designed to improve engagement in HIV care during cancer treatment.
Monthly visits for up to 6 months
Trial Site Locations
Total: 1 location
1
Parirenyatwa Hospital
Harare, Zimbabwe
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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