Training cognitive control in older adults with the space fortress game: the role of training instructions and basic motor ability.
Helena M Blumen, Daniel Gopher, Joshua R Steinerman...
https://pubmed.ncbi.nlm.nih.gov/21120135/Actively Recruiting
Led by Rutgers, The State University of New Jersey · Updated on 2025-12-15
130
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating whether playing a web-based cognitive complex game called the Breakfast Game can improve executive control and multitasking abilities in cognitively healthy older adults aged 60 to 75. This study aims to reduce age-related cognitive decline and the risk of Alzheimers disease or dementia by enhancing important cognitive skills through targeted training. The research is designed as a randomized, double-blind trial with three groups to compare different training approaches and no intervention. Participants will be divided into three groups one will play the Breakfast Game with specific strategy guidance, another will play the game without strategy guidance, and a third will not receive any intervention. Those in the training groups will complete 10 one-hour sessions over 4 weeks, playing the game 2 to 3 times per week. All participants will attend an initial education session on healthy aging, undergo cognitive assessments, health questionnaires, and a blood test before starting. Cognitive assessments will be repeated within 1 to 2 weeks after the intervention and again after three months. During the study, participants will be assessed on changes in their game performance and various cognitive measures related to executive function, attention, and everyday cognition. Questionnaires such as the Everyday Cognition Scale and the Mindful Attention Awareness Scale will be completed at baseline, post-intervention, and at 3-month follow-up. The study includes in-person assessments and online training and follow-up sessions. Safety and cognitive performance will be monitored throughout the study, which lasts about three months after the intervention period.
CONDITIONS
Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study
T
Thamiris Golçalves Clinical Research Coordinator, MS
A
Ana Staniscia Associate Research, MS
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Rutgers, The State University of New Jersey
Lead Sponsor
National Institute on Aging (NIA)
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Training with strategy guidance | Training without strategy (active comparator) | Physical exercise (contextual comparator) |
|---|---|---|---|
| What it is | Web‑based cognitive game training with explicit strategy instructions | Web‑based cognitive game training without strategy instructions | Structured physical exercise programs are widely used to support executive function in healthy older adults |
| Role in trial | Experimental intervention arm | Active comparator arm | Contextual comparator drawn from external standard practice |
| Primary use | To enhance executive control through strategy‑based training | To train cognitive game skills without guided strategy | To maintain or improve executive function through physical activity |
| How it is given or performed | Online game sessions with instructor‑provided strategy guidance | Online game sessions without strategy instructions | Structured physical activity sessions (e.g. aerobic or resistance exercise) offered in research settings |
| Evidence status | Effectiveness under investigation in this randomized trial, benefits not yet established | Under investigation as active comparator, effectiveness not yet determined | Exercise interventions have demonstrated sustained gains in processing speed and reasoning over years in large randomized studies |
| Important risks | Minimal risk beyond standard computer use | Minimal risk beyond standard computer use | Generally safe when tailored but may pose physical risks without screening |
| Important limitations | Benefits depend on user adherence and technology access, and generalizability to non‑computer users is limited | Similar adherence and access concerns, and may offer lower cognitive gains than strategy training | Structured exercise may require physical ability, motivation, and resource access, limiting feasibility for some individuals |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for cognitive assessment, health questionnaires, and blood test
Duration - 4 weeks
Participants in the experimental and active control groups play a complex web-based cognitive training game over multiple sessions to improve executive control and multitasking abilities.
10 one-hour online training sessions over 4 weeks
Duration - Approximately 3 months
Participants complete cognitive assessments to measure the effects of the intervention shortly after treatment and again at 3 months.
2 visits (in-person) for cognitive assessments; one within 1-2 weeks post-intervention and one at 3 months post-intervention
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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Helena M Blumen, Daniel Gopher, Joshua R Steinerman...
https://pubmed.ncbi.nlm.nih.gov/21120135/Sharon Sanz Simon, Daniel Ben-Eliezer, Maria Pondikos...
https://pubmed.ncbi.nlm.nih.gov/37542331/Yaakov Stern, Helena M Blumen, Leigh W Rich...
https://pubmed.ncbi.nlm.nih.gov/21988726/Rutgers, The State University of New Jersey
Lead Sponsor
National Institute on Aging (NIA)
Collaborating Sponsor