Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06936774

Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance

Led by University Hospital, Basel, Switzerland · Updated on 2026-05-06

140

Participants Needed

5

Research Sites

134 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Basel, Switzerland

Lead Sponsor

S

St. Claraspital AG

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical study is to gain further insights into the treatment of patients with Low Anterior Resection Syndrome (LARS) symptoms after rectal resection. The main question is: Can LARS symptoms and quality of life be improved by implementing an intensified follow-up program? Researchers will compare the results of the intervention group with the results of a control group in which patients do not receive an intensified follow-up program to determine whether the intervention works. Participants will undergo an intensified follow-up program which consists of several follow-up visits and medical treatment, pelvic floor muscle training and gynaecological and urological co-treatment in case of LARS symptoms and urinary or sexual complaints.

CONDITIONS

Official Title

Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients older than 18 years
  • Diagnosed with rectal cancer in the middle or lower third of the rectum, stages I to IV
  • Have undergone low anterior resection with total mesorectal excision and protective ileostomy
  • Able to provide informed consent by signing
Not Eligible

You will not qualify if you...

  • Dementia or psychiatric disorders preventing questionnaire completion or effective training
  • Unable to reverse stoma due to persistent anastomotic leak or local cancer recurrence

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Trial Site Locations

Total: 5 locations

1

Clarunis Universitäres Bauchzentrum Basel

Basel, Switzerland, 4002

Actively Recruiting

2

Lindenhofspital Bern

Bern, Switzerland

Actively Recruiting

3

St. Anna Spital Bern

Bern, Switzerland

Not Yet Recruiting

4

Kantonsspital Luzern

Lucerne, Switzerland

Actively Recruiting

5

Kantonsspital Winterthur

Winterthur, Switzerland

Actively Recruiting

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Research Team

F

Felicitas Wiedemann, Resident

CONTACT

M

Marco von Strauss und Torney, Senior physician

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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