Actively Recruiting

Phase Not Applicable
Age: 0 - 2Days
All Genders
NCT06057415

Improving Gastrointestinal Function In High-Risk Newborns By Stimulation Of The Enteric Nervous System

Led by Radboud University Medical Center · Updated on 2024-08-27

200

Participants Needed

1

Research Sites

207 weeks

Total Duration

On this page

Sponsors

R

Radboud University Medical Center

Lead Sponsor

N

Nutricia Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this therapeutical intervention trial is to investigate whether tactile-kinesthaetic and oral sensorimotor stimulation can improve gastrointestional function in preterm infants born before gestational age of 30 weeks and newborns with congenital diaphragmatic hernia. The main question it aims to answer is: • To determine whether HAPTOS- intervention (Handling Adapted to Postnatal age with Tactile-kinaesthetic and Oral sensorimotor Stimulation) in the particpants results in earlier attainment (postnatal days) of full enteral feeding and/or full oral feeding (post menstrual age) compared to standard care. Researchers will compare an intervention group receiving standard of care plus HAPTOS intervention to a group of patients receiving only current standard of care.

CONDITIONS

Official Title

Improving Gastrointestinal Function In High-Risk Newborns By Stimulation Of The Enteric Nervous System

Who Can Participate

Age: 0 - 2Days
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Preterm birth at gestational age less than 30 weeks or
  • Diagnosis of Congenital Diaphragmatic Hernia
  • Born at Amalia Children's Hospital or admitted on first day of life
  • Written informed consent of both parents or representatives
Not Eligible

You will not qualify if you...

  • Preterm infant born at gestational age 30 weeks or more
  • Perinatal asphyxia (Apgar score at 5 minutes less than 5 and first pH 7.0 or less)
  • Major congenital anomalies or birth defects other than congenital diaphragmatic hernia
  • Metabolic disease requiring a special diet other than human milk or formula feeding or with a prognosis of impaired neurological development
  • Parental refusal of participation

AI-Screening

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Trial Site Locations

Total: 1 location

1

Radboud University Nijmegen Medical Centre

Nijmegen, Netherlands, 6500 HB

Actively Recruiting

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Research Team

Y

Yvet Kroeze

CONTACT

V

Viola Christmann, MD,PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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