Actively Recruiting
ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial
Led by University of Alberta · Updated on 2025-11-18
148
Participants Needed
2
Research Sites
205 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
RESILIENCE is 24-week randomized controlled trial that assesses the efficacy of a digital wellness platform, combined with online support from healthcare professionals, to enhance waist circumference and other vital health outcomes in endometrial cancer survivors.
CONDITIONS
Official Title
ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years old
- Histologically confirmed low-grade endometrioid adenocarcinoma, FIGO 2009 stages I to III
- Between 1 month and 10 years after surgery and completion of adjuvant treatment
- Body mass index (BMI) between 25 and 45 kg/m2
- Willing and able to follow study treatments and assessments
- Motivated to achieve best weight according to readiness to change questionnaire
- Own a cell phone compatible with Fitbit app with internet and Bluetooth
- Able to speak, read, and understand English
You will not qualify if you...
- Recurrence or metastatic endometrial cancer
- Abnormal p53 status with FIGO stage III or IV
- Weight changes of 5 kg or more in the last 3 months
- Planned surgery within next 6 months
- Previous bariatric surgery
- Uncontrolled thyroid disorder
- Type 1 diabetes
- Type 2 diabetes with HbA1c over 10% or using insulin, sulfonylureas, or GLP-1 agonists
- Taking corticosteroids or anti-obesity drugs
- Current smoker of any type
- Doing more than 90 minutes per week of moderate aerobic exercise in last 3 months
- Safety risks for exercise or maximal exercise testing
- Physical or mobility issues limiting physical activity
- Following a structured low-calorie or restrictive diet recently, or vegan diet less than 2 years
- History of physician-diagnosed eating disorder
- Planning to be away more than 2 weeks consecutively during study
- Active substance abuse
- Contraindications to DXA or MRI
- Severe hearing or vision loss preventing participation
- Cannot commit to video sessions, lacks internet access, or advised not to lose weight
- Cognitive impairment or dementia
- Unable to come to study site
- Unable to give written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Alberta
Edmonton, Alberta, Canada, T6G 2E1
Actively Recruiting
2
University of Toronto
Toronto, Canada
Actively Recruiting
Research Team
T
Teresita Gormaz, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here