Actively Recruiting
Improving Hepatocellular Carcinoma Screening
Led by Naik Vietti Violi · Updated on 2025-04-03
330
Participants Needed
1
Research Sites
212 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a monocentric, single blind, interventional, single arm study. It is designed to compare the rates of detection of hepatocellular carcinoma (HCC) by ultrasound (US) used in clinical routine vs. abbreviated magnetic resonance imaging (AMRI). The hypothesis is that dynamic AMRI with extracellular contrast agent injection has a higher patient-level detection rate of HCC than screening US and non-contrast AMRI. Interested and eligible patients will be enrolled and undergo HCC screening rounds including US +/- contrast-enhanced US (clinical routine) and screening MRI within the same week bi-annually.
CONDITIONS
Official Title
Improving Hepatocellular Carcinoma Screening
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients with chronic liver disease who need HCC screening according to European Association for the Study of the Liver guidelines
- Signed informed consent form
You will not qualify if you...
- History of hepatocellular carcinoma (HCC)
- History of any other cancer
- Prior liver nodule classified as LI-RAD 4, 5, or M
- History of liver transplantation
- Pregnancy
- Contraindications to MRI or MRI contrast agents
- Any condition that makes the patient unsuitable for the study
- Refusal to share relevant medical information found during study examinations
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Lausanne University Hospital
Lausanne, Canton of Vaud, Switzerland, 1011
Actively Recruiting
Research Team
N
Naik Vietti Violi, MD
CONTACT
C
Clarisse Dromain, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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