Actively Recruiting
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
Led by Glen Foster · Updated on 2025-11-18
10
Participants Needed
2
Research Sites
57 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study examines the effects of low oxygen therapy (LOT) on the stability of 24-hour blood pressure in persons with chronic cervical spinal cord injury. This study will examine if brief episodes of breathing lower oxygen, termed low oxygen therapy (LOT), which has been shown to enhance autonomic nervous system activity, can improve blood pressure stability in individuals with spinal cord injury. The research team will assess 24-hour blood pressure, as well as cardiac, vascular, and autonomic function before and after a 4-day LOT treatment intervention. This study will advance current understanding of treatments to mitigate cardiovascular disease risk in people with spinal cord injuries.
CONDITIONS
Official Title
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Are between the ages of 19-65
- Living with a chronic cervical (at or above T1) spinal cord injury of at least one year
- Are fluent in english
You will not qualify if you...
- High-cervical injuries requiring ventilator assistance to breathe
- Unhealed fracture, contracture, or pressure sore that might interfere with completing the protocol
- Additional concurrent neurological conditions such as multiple sclerosis, Parkinson disease, stroke, or brain injury
- Uncontrolled cardiovascular or pulmonary disease
- Severe neuropathic pain
- Severe recurrent autonomic dysreflexia
- History of seizure disorders
- Known pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
UBC Okanagan
Kelowna, British Columbia, Canada, V1V 1V7
Actively Recruiting
2
International Collaboration on Repair Discoveries (ICORD)
Vancouver, British Columbia, Canada, V5Z 1N1
Actively Recruiting
Research Team
S
Scott F Thrall, M.Sc.
CONTACT
G
Glen E Foster, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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