Actively Recruiting
Improving Hypertension Control in CHina and ARGEntina With a Mobile APP-based Telecare System
Led by Istituto Auxologico Italiano · Updated on 2025-02-27
480
Participants Needed
8
Research Sites
237 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The CHARGE-APP project will investigate whether an innovative management strategy of hypertension based on the combination of usual care visits and ESH CARE App compared to standard care, is associated with differences in outcome, including control rate of office, home and ambulatory BP, cardiovascular and renal intermediate end points at one year, and changes in a number of blood pressure-related variables throughout the study.
CONDITIONS
Official Title
Improving Hypertension Control in CHina and ARGEntina With a Mobile APP-based Telecare System
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female subjects
- Age 18-80 years
- Patient or close person must have a smartphone compatible with the ESH CARE app and be able to use it
- Uncontrolled hypertension with office BP 60;140/90 mmHg and ambulatory 24h ABP 60;130/80 mmHg
You will not qualify if you...
- eGFR less than 45 mL/min/1.73 m2
- Severe uncontrolled hypertension with BP 60;200/120 mmHg despite treatment
- Known secondary hypertension
- Orthostatic hypotension with SBP fall over 20 mmHg on standing
- Unstable clinical conditions or severe disease with short life expectancy
- Known atrial fibrillation
- Hepatic disease with AST or ALT values over 2 times the upper normal limit
- History of gastrointestinal surgery or disorders affecting drug absorption
- History of malignancy including leukemia and lymphoma (except basal cell skin cancer) within 5 years
- History of clinically significant autoimmune disorders like systemic lupus erythematosus
- History of drug or alcohol abuse within 5 years
- History of non-compliance to medical regimens or considered unreliable
- Dementia diagnosis
- Inability or unwillingness to give informed consent
- Inability to use simple communication technologies
- Pregnancy or planned pregnancy during study period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
Private Hospital " Dr Raúl Matera"
Bahía Blanca, Argentina, B8000
Actively Recruiting
2
Argerich Hospital
Buenos Aires, Argentina, C155 AHD
Actively Recruiting
3
General San Martin Hospital of La Plata
La Plata, Argentina, 1900
Actively Recruiting
4
Spanish Hospital of Mendoza
Mendoza, Argentina, M5501
Actively Recruiting
5
British Sanatorium of Rosario
Rosario, Argentina, S2000
Actively Recruiting
6
Shanghai Institute of Hypertension
Shanghai, Huangpu, China
Actively Recruiting
7
Jiangsu Province Official Hospital
Jiangse, China, 210024
Active, Not Recruiting
8
Ruijin Hospital North
Shanghai, China, 200025
Actively Recruiting
Research Team
G
Gianfranco Parati, MD
CONTACT
P
Paulina Wijnmaalen, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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