Actively Recruiting
Improving Nutrition for Babies Born by Caesarean Section
Led by Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · Updated on 2025-11-19
40
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The ambition of the project is to help with the primal colonisation of babies born by caesarean section and to improve the lipid composition of an infant formula, in order to reduce the short- and long-term health problems associated with caesarean births. This population, which represents around 20% of babies born in France, has not yet received any specific care to date. The study aims to develop an optimized infant formula. It includes: (1) isolation of probiotics from breast milk from nursing mothers and stool samples from their babies born vaginally, (2) formulation of an improved milk enriched with physiological lipids and selected probiotics, and (3) preclinical evaluation of its beneficial effects in a cesarean birth model.
CONDITIONS
Official Title
Improving Nutrition for Babies Born by Caesarean Section
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Breastfeeding mothers aged 18 years and older
- Breastfeeding for less than 6 months
- No probiotics taken in the 6 months before sampling
- No antibiotics taken in the 6 months before sampling
- No chronic medical conditions
- Not undergoing chronic treatment
- No history of gestational diabetes
- Body mass index below 25 at the start of pregnancy
- Given consent to participate and for collection of baby's stool samples
- Not deprived of liberty or under guardianship
- Babies under 6 months old
- Born vaginally
- Born at term (at least 37 weeks of pregnancy)
- Exclusively breastfed
- No intrapartum antibiotic treatment
- No known medical conditions
- Not receiving medical supplements other than conventional vitamins
- Babies whose mothers meet the inclusion criteria above
You will not qualify if you...
- Breastfeeding mothers under 18 years old
- Breastfeeding for 6 months or more
- Antibiotic therapy within 6 months before sampling
- Probiotics taken in the 6 months before sampling
- Chronic illness
- Undergoing chronic treatment
- History of gestational diabetes
- Body mass index greater than 25 at the start of pregnancy
- Consent given only for breast milk collection but not baby's stool sample collection
- Deprived of liberty or under guardianship
- Babies older than 6 months
- Born by cesarean section
- Born before 37 weeks of pregnancy
- Not exclusively breastfed
- Received intrapartum antibiotic treatment
- Taking medical supplements other than conventional vitamins
- Having any medical pathology
- Babies whose mothers meet the exclusion criteria above
- Receiving medical supplementation other than conventional vitamins
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
INRAE
Jouy-en-Josas, France, 78350
Actively Recruiting
Research Team
R
REBECA MARTIN-ROSIQUE, PhD
CONTACT
E
ELISE BOREZEE, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here