Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06980701

Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI

Led by The University of Hong Kong · Updated on 2025-12-03

148

Participants Needed

1

Research Sites

53 weeks

Total Duration

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AI-Summary

What this Trial Is About

Prediabetes is an intermediate stage before the development of diabetes, characterized by elevated blood glucose levels but lower than the diagnostic criteria of diabetes and is associated with multiple long-term complications. This systemic disease is mutually linked to inflammatory gum diseases through circulating inflammatory mediators. Controlling inflammatory gum diseases improves blood glucose levels and reduces long-term complications. While maintaining good oral hygiene through home care is essential for managing inflammatory gum diseases, close supervision of patients' home care is labor-intensive and expensive. Artificial Intelligence (AI) has been used to provide personalized advice on the adequacy of patients' home care (oral hygiene). The investigators hypothesize that the use of AI can improve home care, thereby enhancing both gum health and systemic health, similar to human dental professionals.

CONDITIONS

Official Title

Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years and able to give informed consent
  • Mentally and cognitively healthy
  • At least 6 natural front teeth (incisors and canine) in upper or lower jaw
  • Prediabetic with HbA1c 5.7% to 6.4%, fasting plasma glucose 5.6 to 6.9 mmol/L, and/or 2-hour oral glucose tolerance test 7.8 to 11.0 mmol/L
  • Able to speak, read, or understand Cantonese to complete questionnaires
  • Able to perform daily oral hygiene (brushing and interdental cleaning) independently
Not Eligible

You will not qualify if you...

  • Fewer than 6 natural front teeth in upper or lower jaw, with or without dental prostheses
  • Current diagnosis or history of type 2 diabetes
  • Mental illness or similar problems that prevent completing questionnaires
  • Unable to perform oral hygiene due to oral conditions such as tumors or jaw fixation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Prince Philip Dental Hospital

Hong Kong, Sai Ying Pun, Hong Kong, 999077

Actively Recruiting

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Research Team

W

Walter Y.H. Lam, Prof.

CONTACT

M

Mandy M Ho, Prof.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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