Actively Recruiting
Improving the Outcomes of Children With Tuberculosis Through Innovative Diagnostics and Treatment Monitoring
Led by Research Center Borstel · Updated on 2025-02-07
100
Participants Needed
1
Research Sites
80 weeks
Total Duration
On this page
Sponsors
R
Research Center Borstel
Lead Sponsor
L
LMU Klinikum
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims at identifying and evaluating novel diagnostic methods for children evaluated for respiratory tuberculosis. The investigators will use alternative samples like stool, urine, and masks to diagnose children with respiratory tuberculosis. Once diagnosed, the investigators will use target next generation sequencing to determine if the bacillus is resistant to any of the drugs used for treatment. Additionally, children initiated under TB treatment will be followed-up during treatment to measure blood biomarkers for outcome prediction. Finally, spirometry will be performed longitudinally until 3 months after the end of treatment to assess the lung capacity of children treated for respiratory TB. All children initiated on TB treatment will fill in a quality of life questionnaire.
CONDITIONS
Official Title
Improving the Outcomes of Children With Tuberculosis Through Innovative Diagnostics and Treatment Monitoring
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children under 15 years evaluated for respiratory TB.
- Signature of the informed consent form by the parent/guardian and assent form by the child if applicable.
You will not qualify if you...
- Refusal to sign informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Marius Nasta Institute of Pneumology
Bucharest, BUC, Romania, 050159
Actively Recruiting
Research Team
A
Anca Vasiliu, MD, PhD
CONTACT
D
Dragos Baiceanu, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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