Actively Recruiting
Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment
Led by University of Arkansas · Updated on 2026-03-30
10
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
Sponsors
U
University of Arkansas
Lead Sponsor
N
National Center for Advancing Translational Sciences (NCATS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Drug overdose is a leading cause of death among postpartum women and opioid-related mortality is 4 times higher in the postpartum period when compared to the third trimester of pregnancy. Medications for opioid use disorder (MOUD; e.g., methadone or buprenorphine) are the recommended standard of care for perinatal women with OUD. Studies indicate that 50-60% of perinatal women with OUD initiate medications during pregnancy; however, over half will prematurely discontinue treatment within the first six months of childbirth due to stressors experienced in the postpartum period. Common stressors that contribute to MOUD treatment discontinuation in this population are return to opioid use, mental health symptoms including depression, parenting-related stressors such as challenges in infant care and bonding, Neonatal Abstinence Syndrome (NAS), child welfare involvement, and feelings of guilt, shame, and stigma. Thus, there is an urgent need to develop effective, recovery-oriented support interventions that promote the initiation and continuity of MOUD treatment in the postpartum period. The current study utilizes community-engaged research methods to identify and prioritize the early parenting-related needs of postpartum women receiving MOUD to inform the adaptation and implementation of an evidence-based parenting intervention for this population receiving outpatient treatment for opioid use disorder.
CONDITIONS
Official Title
Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Understand and speak English
- Able to give informed consent
- Receiving medications for opioid use disorder in the outpatient clinical setting
- Between 28 weeks gestation and up to 12 months postpartum
You will not qualify if you...
- Unwilling to consent
- Before 28 weeks gestation and beyond 12 months postpartum at enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
Actively Recruiting
Research Team
M
Mollee K Steely Smith, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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