Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT07071766

Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment

Led by University of Arkansas · Updated on 2026-03-30

10

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

Sponsors

U

University of Arkansas

Lead Sponsor

N

National Center for Advancing Translational Sciences (NCATS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Drug overdose is a leading cause of death among postpartum women and opioid-related mortality is 4 times higher in the postpartum period when compared to the third trimester of pregnancy. Medications for opioid use disorder (MOUD; e.g., methadone or buprenorphine) are the recommended standard of care for perinatal women with OUD. Studies indicate that 50-60% of perinatal women with OUD initiate medications during pregnancy; however, over half will prematurely discontinue treatment within the first six months of childbirth due to stressors experienced in the postpartum period. Common stressors that contribute to MOUD treatment discontinuation in this population are return to opioid use, mental health symptoms including depression, parenting-related stressors such as challenges in infant care and bonding, Neonatal Abstinence Syndrome (NAS), child welfare involvement, and feelings of guilt, shame, and stigma. Thus, there is an urgent need to develop effective, recovery-oriented support interventions that promote the initiation and continuity of MOUD treatment in the postpartum period. The current study utilizes community-engaged research methods to identify and prioritize the early parenting-related needs of postpartum women receiving MOUD to inform the adaptation and implementation of an evidence-based parenting intervention for this population receiving outpatient treatment for opioid use disorder.

CONDITIONS

Official Title

Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Understand and speak English
  • Able to give informed consent
  • Receiving medications for opioid use disorder in the outpatient clinical setting
  • Between 28 weeks gestation and up to 12 months postpartum
Not Eligible

You will not qualify if you...

  • Unwilling to consent
  • Before 28 weeks gestation and beyond 12 months postpartum at enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States, 72205

Actively Recruiting

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Research Team

M

Mollee K Steely Smith, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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