Actively Recruiting
Improving Personalized Treatment in Oncology: Effects of Integrated Oncological Decision-making
Led by Leiden University Medical Center · Updated on 2025-07-02
400
Participants Needed
4
Research Sites
100 weeks
Total Duration
On this page
Sponsors
L
Leiden University Medical Center
Lead Sponsor
D
Dutch Cancer Society
Collaborating Sponsor
AI-Summary
What this Trial Is About
The research aims to evaluate an Integrated Oncological Decision-making Model (IODM) to tailor oncological treatment plans to individual patients. The primary objective is to assess the impact of the IODM on personalized decision-making and patient outcomes. The study will employ a stepped-wedge cluster randomized trial design involving eight oncological care paths across four medical centers in the Netherlands. The study population consists of 400 adult patients (50 per care path) who will undergo treatment based on either standard clinical guidelines (control) or the IODM (intervention). The intervention involves integrating three key components: oncological treatment options, patient's general health status, and patient's goals and preferences. The main study parameters include measuring the discordance between recommendations based on medical information and final treatment decisions, assessing whether discordance reflects more personalized decision-making, and evaluating the implementation process of the IODM.
CONDITIONS
Official Title
Improving Personalized Treatment in Oncology: Effects of Integrated Oncological Decision-making
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient's age 18 years or older
- Patient is included in a participating oncological care path
- Patient does not yet have a treatment plan
- Patient, partner, or caregiver reads and speaks Dutch well enough to understand the research material and complete questionnaires
- Patient must be able to participate in the decision-making process
You will not qualify if you...
- Patient, partner, or caregiver cannot give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
University Medical Center Groningen (UMCG)
Groningen, Netherlands, 9713GZ
Actively Recruiting
2
Leiden University Medical Center (LUMC)
Leiden, Netherlands, 2333ZB
Actively Recruiting
3
Maastricht University Medical Center
Maastricht, Netherlands, 6229 HX
Actively Recruiting
4
Zuyderland MC
Sittard, Netherlands, 6162 BG
Actively Recruiting
Research Team
L
Lieke Welling, MD PhD (Dr)
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here