Actively Recruiting
Evaluating the Integrated Oncological Decision-making Model to Personalize Cancer Treatment Decisions in Adult Patients
Led by Leiden University Medical Center · Updated on 2025-07-02
400
Participants Needed
4
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating an Integrated Oncological Decision-making Model IODM designed to tailor cancer treatment plans to individual patients. This study aims to assess how the IODM affects personalized treatment decisions and patient outcomes. The trial uses a stepped-wedge cluster randomized design involving 400 adult patients across eight oncological care paths in four medical centers in the Netherlands. Participants will receive either usual care based on standard clinical guidelines or care using the IODM, which integrates three components current oncological treatment options with their benefits and risks, the patients overall health including physical and emotional functioning, and the patients goals and preferences in treatment and daily life. The study transitions care paths from standard practice to the IODM in randomized steps. Throughout the study, researchers will assess the difference between standard treatment recommendations and actual decisions, focusing on whether these differences reflect more personalized choices. They will also evaluate patient quality of life, frailty, resilience, optimism, decision-making preferences, and patient-centeredness using questionnaires and medical records. The study duration includes the intervention and a 12-month follow-up, totaling around two years.
CONDITIONS
Brief Title
Improving Personalized Treatment in Oncology: Effects of Integrated Oncological Decision-making
Research Team
L
Lieke Welling, MD PhD (Dr)
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
