Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06082518

Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments

Led by Sunnybrook Health Sciences Centre · Updated on 2026-03-16

40

Participants Needed

1

Research Sites

173 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Over 500 million people have been infected with COVID-19, and to date, more than 6 million people have died. Many individuals who have recovered from COVID-19 continue to experience symptoms even after they have been "cured" of the disease. This condition is known as post COVID-19 condition, which can have serious health consequences. A common symptom among these individuals is chronic fatigue, characterized by persistent tiredness or lack of energy. This study aims to explore a novel treatment for symptoms of post COVID-19 condition, known as hyperbaric oxygen therapy. This approach has shown promise in helping people with post COVID-19 conditions and treating some other causes of fatigue. Hyperbaric oxygen therapy involves placing patients in a small chamber where they receive high oxygen gas levels. However, this treatment is expensive and time-consuming, and it is unclear if this treatment can be effectively assessed in a large-scale research study. This small study will help us decide if conducting a large research study is feasible. The investigators aim to assess if hyperbaric oxygen therapy can improve symptoms of post COVID-19 condition, such as fatigue.

CONDITIONS

Official Title

Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Official diagnosis of post COVID-19 condition by a healthcare practitioner
  • At least 3 months since SARS-CoV-2 infection
  • Persistent symptoms lasting more than 12 weeks including chronic fatigue plus one of the following: difficulty thinking or problem solving ('brain fog'), stress, or anxiety
Not Eligible

You will not qualify if you...

  • Medical conditions preventing safe hyperbaric treatment (e.g., pneumothorax, active unstable coronary disease)
  • Cognitive difficulties or mental retardation before COVID diagnosis
  • History of traumatic brain injury
  • Unlikely to comply with follow-up assessments (e.g., no fixed address, plans to move away)
  • Known pregnancy or planning pregnancy in women of childbearing age

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada, M4N3M5

Actively Recruiting

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Research Team

F

Fahad Alam, MD

CONTACT

L

Lilia Kaustov, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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