Actively Recruiting
Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
Led by University Health Network, Toronto · Updated on 2025-12-03
104
Participants Needed
1
Research Sites
678 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Although chest wall recurrence of breast cancer is uncommon, it represents a difficult clinical scenario. The role of full thickness chest wall resection (FTCWR) for breast cancer recurrence in the chest wall is controversial and is complicated by the fact that no prospective evidence exists evaluating the utility of FTCWR in prolonging survival or improving health related quality of life (HRQOL) and thus, there is a lack of evidence to guide treatment decisions. Gathering HRQOL, local-regional recurrence (LRR) and survival data in a prospective fashion is thus critical in this population. Therefore, we designed a prospective trial to evaluate the outcomes for FTCWR in terms of LRC and HRQOL, and short-term morbidity and mortality, with secondary focus on potential long-term overall survival benefit.
CONDITIONS
Official Title
Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years of age
- Breast cancer invading the chest wall confirmed by imaging
- Breast cancer invasion confirmed by tissue biopsy
- Medically fit for surgery
- More than 1 year disease-free interval since initial treatment for local recurrence
You will not qualify if you...
- Medically inoperable due to other health problems or contraindications
- Disease that cannot be surgically removed
- Not eligible for chemotherapy
- Eastern Cooperative Oncology Group (ECOG) performance status greater than 2
- Patient refusal to participate
AI-Screening
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Trial Site Locations
Total: 1 location
1
University Health Network (Toronto General Hospital and Princess Margaret Cancer Centre)
Toronto, Ontario, Canada, M5G 2C4
Actively Recruiting
Research Team
J
Jennifer Lister, BSc CCRP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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