National iCARE Study to Understand and Improve Kidney Problems in Youth with Type 2 Diabetes

What this Trial Is About

Researchers are studying youth diagnosed with type 2 diabetes to understand the main biological, psychological, and social BPS risk factors that contribute to kidney damage, specifically albuminuria. The study aims to identify how these risk factors, including poor blood sugar control, high blood pressure, stress, and social challenges, influence kidney problems and whether inflammation is a key link in this process. The study follows a group of 500 young people diagnosed with type 2 diabetes before age 18 over two years. Researchers will analyze various biological, psychological, and social factors and use advanced statistical methods to understand their relationships with kidney damage. This observational study will not test treatments but will gather detailed information to clarify these risk factors. Participants will undergo assessments including blood and urine tests to measure kidney function and inflammation, as well as evaluations of their physical, psychological, and social health. Researchers will track changes in albumin levels and kidney filtration rates over two years. The study involves regular monitoring to better understand the progression of kidney issues in youth with type 2 diabetes.

Improving Renal Complications in Adolescents With Type 2 Diabetes Through REsearch Cohort Study (National iCARE Study)