Actively Recruiting
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
Led by University of South Florida · Updated on 2026-04-21
165
Participants Needed
1
Research Sites
185 weeks
Total Duration
On this page
Sponsors
U
University of South Florida
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
CONDITIONS
Official Title
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Willing to be randomized
- Able to read and understand English
- Diagnosed with chronic widespread pain and insomnia
- Prescribed opioid medication for at least 1 month, taken 3 or more times per week
- Desire to reduce or eliminate opioid use
- Written agreement from the prescribing physician for opioid medication
- Not using prescribed or over-the-counter sleep medications for at least 1 month, or stabilized on sleep medications for 6 or more weeks
You will not qualify if you...
- Unable to provide informed consent
- Cognitive impairment (Mini-Mental State Exam score less than 26)
- Sleep disorders other than insomnia, including sleep apnea (apnea/hypopnea index greater than 15) or Periodic Limb Movement Disorder (myoclonus arousals per hour greater than 15)
- Bipolar disorder or seizure disorder
- Severe untreated major mental health conditions besides depression or anxiety, such as suicidal thoughts or psychotic disorders
- Use of psychotropic or other medications that affect pain or sleep, except those prescribed specifically for pain or sleep
- Participation in other non-drug treatments for pain, sleep, or mood outside this trial
- Presence of internal metal objects or electrical devices
- Pregnancy
- Presumptive or confirmed lumbar nerve root compression
- Confirmed lumbar spinal stenosis
- Less than 6 months since back surgery
- Other spinal disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of South Florida
Tampa, Florida, United States, 33612
Actively Recruiting
Research Team
C
Christina S McCrae, PhD
CONTACT
B
Britani Holland, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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