Actively Recruiting
Improving Status Epilepticus Treatment Times
Led by Nationwide Children's Hospital · Updated on 2026-04-01
450
Participants Needed
1
Research Sites
164 weeks
Total Duration
On this page
Sponsors
N
Nationwide Children's Hospital
Lead Sponsor
C
Children's Hospital of Philadelphia
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a stepped-wedge cluster randomized effectiveness-implementation hybrid study aimed at determining the effect of dissemination of a QI bundle on the time to treatment of SE among hospitalized, non-critically ill children. The primary study endpoint is to decrease the time from the SE diagnosis to treatment with the first dose of a benzodiazepine (BZD) as measured during hospitalization, which will decrease chances of morbidity and mortality.
CONDITIONS
Official Title
Improving Status Epilepticus Treatment Times
Who Can Participate
Eligibility Criteria
You may qualify if you...
- SE episode occurs in a male or female child aged between > 30 days to < 19 years
- Seizures meeting at least one of these: continuous clinically apparent seizure lasting more than 5 minutes
- Continuous clinically apparent seizure of any duration receiving benzodiazepines
- Repeated seizures without return to neurological baseline within 5 minutes
You will not qualify if you...
- SE episode occurs in a child with infantile spasms
- SE episode occurs in a child with electrographic-only seizures without clinical signs other than encephalopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205
Actively Recruiting
Research Team
A
Adam Ostendorf, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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