Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06298721

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

Led by The Cleveland Clinic · Updated on 2025-05-18

300

Participants Needed

1

Research Sites

154 weeks

Total Duration

On this page

Sponsors

T

The Cleveland Clinic

Lead Sponsor

A

American Association of Hip and Knee Surgeons

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline mental health and poor physical function, improves satisfaction at 1-year (when compared to standard of care).

CONDITIONS

Official Title

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult subject (Age >18 and < 80 years of age)
  • Proficient in the English language
  • Willing to voluntarily sign the Informed Consent Form
  • Scheduled for a unilateral primary total knee arthroplasty (TKA)
  • TKA PROMs phenotypes indicate higher risk of dissatisfaction
  • Willing and able to complete all required follow-up procedures
Not Eligible

You will not qualify if you...

  • Requires simultaneous or staged bilateral knee replacements less than 90 days apart
  • Undergoing revision total knee arthroplasty (TKA)
  • Has inflammatory arthritis
  • History of infection in the joint undergoing TKA
  • Considered a member of a protected population (e.g., prisoner, mentally incompetent)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

S

Shujaa T Khan, MD

CONTACT

A

Alison Klika

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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