Actively Recruiting

Age: 18Years +
All Genders
NCT05756985

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

Led by Baptist Health South Florida · Updated on 2026-02-04

120

Participants Needed

1

Research Sites

211 weeks

Total Duration

On this page

Sponsors

B

Baptist Health South Florida

Lead Sponsor

M

Miami Cancer Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

To collect and preserve glioblastoma tissue during standard of care tumor resection surgery and blood for future molecular and genetic testing. Tissue for research will be collected from three different regions within the same tumor to study how these regions differ in their structure, DNA, and RNA and also to compare the data obtained from this testing to imaging data found in the medical record. The goal of this study is to help us better understand what the glioblastoma tumor tissue looks like and how it functions. This understanding can lead to new therapies for the treatment of glioblastoma in the future.

CONDITIONS

Official Title

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have the appearance of high-grade glioma on MRI and will undergo surgery if confirmed as glioblastoma or gliosarcoma
  • Patients with confirmed glioblastoma or gliosarcoma having repeat surgery for a recurrent tumor
  • Aged 18 years or older
  • Tumor volume of at least 10 cc on MRI within 1 month prior to surgery
  • Signed and dated informed consent by participant or legal representative
Not Eligible

You will not qualify if you...

  • History or current evidence of medical conditions, therapies, or lab abnormalities that could affect study results or are not in the participant's best interest according to the investigator

AI-Screening

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Trial Site Locations

Total: 1 location

1

Miami Cancer Institute at Baptist Health, Inc.

Miami, Florida, United States, 33176

Actively Recruiting

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Research Team

M

Manmeet S Ahluwalia, M.D.

CONTACT

M

Michael McDermott, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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