Actively Recruiting

Early Phase 1
Age: 21Years - 25Years
All Genders
Healthy Volunteers
NCT05929677

Impulsivity Domains and Subjective Response

Led by Jessica Weafer · Updated on 2026-02-05

250

Participants Needed

2

Research Sites

178 weeks

Total Duration

On this page

Sponsors

J

Jessica Weafer

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Findings from this project will determine the relationship between two vulnerability factors for Alcohol Use Disorder (AUD) in young adults: impulsivity and subjective response to alcohol. The results will identify badly needed, novel targets for prevention and treatment efforts to simultaneously reduce impulsivity and subjective responses in at-risk young adults.

CONDITIONS

Official Title

Impulsivity Domains and Subjective Response

Who Can Participate

Age: 21Years - 25Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 21 and 25 years
  • Report drinking to an estimated blood alcohol concentration above 0.08% at least once in the past 30 days
  • Report drinking alcohol at least twice a week in the past 30 days
  • Fluent in English
Not Eligible

You will not qualify if you...

  • Serious medical problems such as liver disease, cardiac abnormalities, pancreatitis, diabetes, neurological problems, or gastrointestinal disorders
  • Body weight less than 110 pounds or more than 210 pounds
  • Axis I psychiatric disorders except mild or moderate alcohol use disorder or mild cannabis use disorder
  • Current alcohol withdrawal or history of medically-assisted detoxification
  • Two positive breath alcohol concentration readings above 0.00% at screening or experimental sessions
  • Positive urine test for illegal drugs other than cannabis
  • Currently seeking or history in the past 12 months of inpatient or intensive treatment for addictive behaviors
  • Current use or prescription of psychotropic medications in the past 30 days
  • Psychosis or other psychiatric disabilities
  • Pregnancy, nursing, or lack of reliable birth control use for women
  • Smoking more than 5 cigarettes per day

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Northeastern University

Boston, Massachusetts, United States, 02115

Actively Recruiting

2

Ohio State University

Columbus, Ohio, United States, 43221

Actively Recruiting

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Research Team

J

Jessica Weafer, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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Impulsivity Domains and Subjective Response | DecenTrialz