Actively Recruiting

Age: 18Years - 65Years
All Genders
NCT07320066

IMT in Asthma: Activity, Coping, Self-Management

Led by Istanbul Esenyurt University · Updated on 2026-01-09

15

Participants Needed

1

Research Sites

101 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to investigate asthma patients' experiences with an 8 week IMT and the perceived effects of this intervention on physical activity, coping strategies, and asthma self-management. A qualitative methodological design will be applied to understand the experiences of patients participating in the IMT program, how the program affected their daily activities, how they coped with symptoms and difficulties, and how they managed their condition.

CONDITIONS

Official Title

IMT in Asthma: Activity, Coping, Self-Management

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Being between the ages of 18-65
  • Diagnosed with severe persistent, non-allergic asthma by a pulmonologist following GINA guidelines
  • Presence of type 2 inflammation markers: peripheral eosinophils <150/µL and/or negative skin prick test and/or total IgE <30 kU/L
  • Showing bronchodilator response (>12% or 200 mL improvement in FEV1% predicted after inhaling 400 mg salbutamol)
  • Diagnosed at least 6 months prior and under follow-up and treatment or having controlled asthma
  • Completed the pulmonary rehabilitation program
  • Completed 8 weeks of inspiratory muscle training (IMT)
  • Read, understood, and signed the informed consent form
Not Eligible

You will not qualify if you...

  • Recent respiratory tract infection within the last month
  • Smoking history over 10 pack-years or smoking within 6 months after quitting
  • Oral corticosteroid treatment in the last 4 weeks
  • Body Mass Index greater than 35
  • Diagnosed with Eosinophilic Granulomatosis Polyangiitis (EGPA) or Allergic Bronchopulmonary Aspergillosis (ABPA)
  • Vasculitis
  • History of malignancy
  • Pregnancy
  • Previous lung surgery or use of long-term oxygen therapy
  • Presence of restrictive lung diseases (like advanced kyphoscoliosis, ankylosing spondylitis) or neuromuscular diseases (such as myasthenia gravis, muscular dystrophies, myopathies) preventing healthy respiratory testing and rehabilitation
  • Cognitive dysfunction, mental retardation, dementia, or other conditions making protocol adherence difficult
  • Unwillingness to continue participating
  • Communication difficulties or intellectual disabilities

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istanbul Esenyurt University

Istanbul, Istanbul, Turkey (Türkiye), 34890

Actively Recruiting

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Research Team

E

Esra PEHLİVAN, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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