Actively Recruiting
INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)
Led by RAND · Updated on 2025-09-11
550
Participants Needed
1
Research Sites
239 weeks
Total Duration
On this page
Sponsors
R
RAND
Lead Sponsor
A
Arizona State University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Low medication adherence when initiating antiretroviral treatment (ART) is a key barrier to HIV virologic suppression, resulting in avoidable cases of drug resistance, death, and viral transmission. Routinized pill-taking can lead to successful long-term ART adherence, and short-term behavioral economics-based supports are a novel way to overcome the limited success of existing routinization interventions. This study proposes to test this combined approach for promoting long-term ART adherence using a Stage III Sequential, Multiple Assignment, Randomized Trial (SMART) design in one of the largest HIV clinics in Uganda to identify the most cost-effective adaptive intervention that if found effective is generalizable to other settings and other chronic diseases.
CONDITIONS
Official Title
INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female clients age 18 and older
- Started ART at Mildmay or another clinic within the preceding 2 months
- Able to speak and understand either English or Luganda
- Have their own cell phone or have consistent access to someone else's phone
- Willing to receive daily text messages for the 6 months of intervention duration
- Willing and able to use the WisePill device distributed for adherence verification for the duration of the study
You will not qualify if you...
- Not mentally fit to consent
- Language other than Luganda or English
- Not willing to consistently use the WisePill device for adherence measurement
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Mildmay Uganda
Kampala, Uganda, 24985
Actively Recruiting
Research Team
Y
Yvonne Karamagi Site Principal Investigator
CONTACT
L
Lillian Lukuse
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
4
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