Actively Recruiting
Incidence of Acute Kidney Injury After Administration of Iodine Contrast Media in Patients With Reduced Renal Function
Led by Uppsala University · Updated on 2024-05-20
400
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is examining if injection of iodine contrast media increases the risk of acute kidney injury in patients with severely reduced renal function. All patients who have a medical need for a computerized tomography, either with or without iodine contrast media, and has a renal function of less than estimated glomerular filtration rate (eGFR) 30 will be recruited. Blood and urine samples will be collected at baseline, three and 21 days after the computerized tomography. Additionally, we will examine if the decision to use iodine contrast media or not was easy or difficult if the use of iodine contrast media potentially changed the patient care and if it might have been lifesaving.
CONDITIONS
Official Title
Incidence of Acute Kidney Injury After Administration of Iodine Contrast Media in Patients With Reduced Renal Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- eGFR less than 30 mL/min/1.73m2 calculated using the revised Lund-Malm�f6 formula and plasma creatinine
- Medical need for either an iodine contrast media (ICM)-enhanced or unenhanced computerized tomography (CT) scan
You will not qualify if you...
- Under 18 years of age
- Receiving ongoing renal replacement therapy
- Currently treated with nephrotoxic drugs including acyclovir, aminoglycosides, ciclosporins, cisplatin, methotrexate, non-steroidal anti-inflammatory drugs (except low-dose aspirin), or intravenous vancomycin
- Known allergy to iodine contrast media without receiving prophylactic treatment (for patients in the ICM group)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Uppsala University
Uppsala, Sweden, 751 85
Actively Recruiting
Research Team
F
Felix B Berglund, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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