Actively Recruiting
Incidence and Determinants of Joint Contractures in Mechanically Ventilated Intensive Care Unit Patients: a Prospective Cohort Study
Led by Elazıg Fethi Sekin Sehir Hastanesi · Updated on 2026-01-14
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how often and why joint contractures develop in adults who are mechanically ventilated and immobilized in the intensive care unit (ICU). This observational study focuses on patients with impaired consciousness and explores how prolonged immobilization, sedation, and muscle relaxation may lead to joint stiffness that affects recovery and rehabilitation after ICU discharge. Adult patients admitted to the ICU who are mechanically ventilated and immobilized will be enrolled within 48 hours of admission. They will receive standard ICU care and physiotherapy, including positioning and joint exercises. Joint motion will be measured twice weekly using a goniometer to detect any reduction of at least 33% compared to normal movement. No experimental treatments will be given during the study. Participants will be followed throughout their ICU stay, with data collected on demographics, clinical factors, and ICU treatments. Researchers will track the incidence and timing of joint contractures and analyze factors linked to their development. Assessments will continue for up to 28 days or until ICU discharge or death, aiming to provide insights for better prevention and rehabilitation strategies in critical care.
CONDITIONS
Brief Title
Incidence and Determinants of Joint Contractures in Mechanically Ventilated ICU Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 18 and over
- Patients on mechanical ventilation and monitored in the intensive care unit for at least 7 days
- Glasgow Coma Score of 10 or less
- Patients monitored immobile in the intensive care unit
- Situations where informed consent can be obtained from the patient's legal representative
You will not qualify if you...
- Presence of pre-existing joint contracture, ankylosis, or amputation
- Patients with severe burns, fractures, or surgical reasons preventing joint movement
- Patients with a history of neuromuscular disease or spasticity
- Patients who were immobilized for 1 week or more prior to admission to the intensive care unit
- Hemodynamic instability situations where measurement is unreliable
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - Up to 48 hours after ICU admission
Participants are screened for eligibility to participate in the trial.
1 screening visit (in-person)
Duration - Up to 28 days or until ICU discharge or death
Participants who are mechanically ventilated and immobilized in the ICU are observed. Joint range of motion is measured twice weekly to assess for joint contracture development. Participants receive routine ICU care including standard physiotherapy.
Twice weekly visits for joint range of motion measurements
Trial Site Locations
Total: 1 location
1
Fethi Sekin City Hospital
Elâzığ, Elaziğ, Turkey (Türkiye), 23050
Actively Recruiting
Research Team
S
Sevim F Şenol Karataş, MD, PhD
S
Sevim Şenol Karataş, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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