Actively Recruiting
Incidence and Impact of ICU-acquired Diaphragm Weakness
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-05-28
194
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
ICU survivors are at an increased risk of hospital and ICU readmission. Among the complications of ICU stay, diaphragmatic dysfunction is common, with a prevalence of 60 to 80%, and is associated with increased mortality and prolonged hospital stays. Furthermore, several studies have reported that the observation of impaired respiratory muscle function upon ICU discharge is associated with a poor long-term prognosis. However, the incidence and prognostic impact of persistent diaphragmatic dysfunction at ICU discharge have never been evaluated. The measurement of dyspnea, a composite evaluation of respiratory muscle function, has not been assessed for predicting prognosis upon ICU discharge. The hypothesis of the project is that the presence of ICU-acquired diaphragmatic dysfunction at ICU discharge is associated with a poorer prognosis within 90 days.
CONDITIONS
Official Title
Incidence and Impact of ICU-acquired Diaphragm Weakness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Received invasive or non-invasive respiratory support for at least 48 hours
- Weaned from respiratory support within the last 24 hours
- Patient or trusted person informed about the study and not opposed to participation
You will not qualify if you...
- Known pre-existing diaphragmatic dysfunction such as phrenic nerve injury or neuromuscular disease
- Presence of a tracheostomy
- Unable to communicate
- Legally protected individuals under guardianship or deprived of liberty by court or administrative order
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Médecine intensive Réanimation
Paris, France, 75013
Actively Recruiting
Research Team
M
Martin Dres, MD,PHD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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