Actively Recruiting
Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2024-07-10
170
Participants Needed
3
Research Sites
304 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Neutropenia after induction or consolidation therapy for acute myeloid leukemia (AML) patients is associated with a high morbi-mortality rates, especially due to infectious complications. These are managed according to international recommandations (ECIL and IDSA) with antibiotherapy and antifungal strategy. Although the patients suffer of digestive symptoms, intestinale complications are really less explored. Neutropenic enterocolitis (NE), cytomegalovirus (CMV) colitis, Clostridium difficile colitis, specific lesion, ischemic colitis are not well-known. No prospective study evaluate NE and these digestive complications which have high morbi-mortality rates.
CONDITIONS
Official Title
Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Able to receive intensive treatment for AML (induction then intensive consolidations) causing neutropenia with high infectious risk
- Able to provide informed consent
- Affiliated to a social security system
You will not qualify if you...
- Patients under 18 years old
- Patients with AML who cannot receive intensive therapy
- Patients with acute promyelocytic leukemia
- Pregnant women
- Patients with HIV, hepatitis B, or hepatitis C
- Patients under guardianship or deprived of freedom by court or administrative order
AI-Screening
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Trial Site Locations
Total: 3 locations
1
CHU Amiens-Picardie
Amiens, France, 80000
Not Yet Recruiting
2
CHU de Caen
Caen, France, 14033
Not Yet Recruiting
3
Henri Becquerel Center
Rouen, France, 76038
Actively Recruiting
Research Team
D
Delphine LEBON, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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