Actively Recruiting
Incidence of Postoperative Cognitive Decline in Patients With Preexisting Cognitive Impairment
Led by Peking University Shenzhen Hospital · Updated on 2025-08-22
340
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to find out how often memory and thinking problems happen after surgery in people who already have memory issues before their operation. These memory problems are called postoperative cognitive decline (POCD). Older adults with memory problems before surgery may be more likely to have trouble with thinking, memory, and daily activities after their operation. This study will follow patients who already have memory problems before surgery and see how their thinking and memory change after surgery. The results will help doctors better understand how to care for these patients before, during, and after surgery.
CONDITIONS
Official Title
Incidence of Postoperative Cognitive Decline in Patients With Preexisting Cognitive Impairment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 60 years or older
- Mild cognitive impairment or mild dementia confirmed by MMSE and MoCA-B tests before surgery
- Undergoing elective non-cardiac surgery under general anesthesia
- For normative group: age 60 years or older
- For normative group: Mini-Cog score greater than 1
- For normative group: No history of general anesthesia surgery in past 12 months
You will not qualify if you...
- Difficulty completing cognitive assessments such as inability to communicate in Mandarin, blindness, or deafness
- Usual residence outside Shenzhen
- For normative group: planned elective surgery under general anesthesia within next 12 months
- For normative group: history or screening indicating cognitive impairment by MMSE and MoCA-B
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking University Shenzhen Hospital
Shenzhen, Guangdong, China
Actively Recruiting
Research Team
Y
Yaqian Yu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here