Actively Recruiting
Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery
Led by Sir Ganga Ram Hospital · Updated on 2026-04-27
270
Participants Needed
2
Research Sites
398 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Postoperative delirium (POD) is the most common adverse neurologic complication that can occur in patients of any age. Its incidence varies across age groups and is substantially influenced by patient-related risk factors. POD occurs in 17%-61% of major surgical procedures. Several risk factors which contribute to the development of POD include age more than 60 years, pre-existing cognitive dysfunction, presence of comorbidities, sensorial deficits, malnutrition, polypharmacy, impaired physical mobility and frailty. Postoperative delirium has several wide ranging and adverse outcomes that are consistently associated with delirium such as mortality, increased length of hospital stay, and increased hospital costs. A recently devised tool for rapid assessment of delirium is the 4 A's test. It has now been validated for identifying delirium in the surgical population. The proposed prospective observational study will be conducted on 150 patients belonging to ASA Physical Status I-III of either sex, scheduled to undergo non-cardiac surgery under general anaesthesia (GA), requiring at least 24 hours of postoperative inpatient care. This prospective, observational study aims to evaluate the incidence, risk factors and outcomes of postoperative delirium in elderly patients more than 65 years of age undergoing non-cardiac surgery.
CONDITIONS
Official Title
Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged over 65 years
- Both male and female patients
- ASA physical status I to III
- Scheduled for elective non-cardiac surgery under general anesthesia
- Clinical Frailty Score between 1 and 8
- Require at least 24 hours of postoperative inpatient care
You will not qualify if you...
- Clinical Frailty Score of 9
- Diagnosis of dementia, severe psychiatric, or neurological diseases
- Surgery within the past 3 months
- Head injury within the past 3 months
- Uncompensated cardiovascular disease, hepato-renal insufficiency, or uncontrolled endocrine disease
- Use of antidepressant, anti-anxiety, anticonvulsant, or antiparkinsonism medications
- Preoperative hemoglobin less than 8 gm % or serum albumin less than 3.5 mg/dl
- Unable to give informed consent
- Presence of preoperative delirium (4 A's Test score of 4 or higher)
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Sir Ganga Ram Hospital
New Delhi, National Capital Territory of Delhi, India, 110060
Actively Recruiting
2
Sir Ganga Ram Hospital
New Delhi, India, 110060
Not Yet Recruiting
Research Team
B
Bimla Sharma, MBBS, DGO, MD, FICA, MHA
CONTACT
N
Nitin Sethi, MBBS, DNB
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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