Actively Recruiting

Age: 20Years - 40Years
FEMALE
NCT07443345

Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia

Led by Cairo University · Updated on 2026-03-11

52

Participants Needed

1

Research Sites

42 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.

CONDITIONS

Official Title

Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia

Who Can Participate

Age: 20Years - 40Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with severe preeclampsia undergoing cesarean section
  • Gestational age > 32 weeks
  • Female patients aged between 20 and 40 years
Not Eligible

You will not qualify if you...

  • Age less than 20 years
  • Diabetes
  • Neuromuscular diseases
  • Patient refusal to participate
  • Contraindications to magnesium sulphate administration
  • Inability to obtain adequate ultrasound views

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cairo University Hospitals

Cairo, Egypt

Actively Recruiting

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Research Team

M

Mina Adolf Helmy, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia | DecenTrialz