Study of Residual Muscle Relaxants and Frailty in Women Undergoing Gynecologic Cancer Surgery

What this Trial Is About

This research aims to understand how frailty affects patients undergoing gynecologic cancer surgery, including vulvar, endometrial, and ovarian cancers. Frailty is linked with higher risks of complications, longer hospital stays, and increased mortality. The study specifically investigates how leftover neuromuscular blocking drugs after surgery relate to frailty in these patients, a connection not previously studied in gynecologic oncology. Participants will receive a nerve stimulation test called Train of Four TOF using specialized equipment in the recovery room after surgery to detect residual muscle relaxants. The study will observe these patients from just before surgery up to a year after, collecting data on the presence of frailty, anesthesia methods, blood transfusions, use of blood pressure medications, and various postoperative outcomes including complications and mortality. Throughout the study, patients will be monitored closely with assessments of neuromuscular blockade within 30 minutes after surgery and frailty checks within 24 hours before surgery. Researchers will track hospital stay length, intensive care admissions, mechanical ventilation use, and pulmonary issues up to 30 days post-operation. This comprehensive follow-up will help clarify how frailty and residual muscle relaxants impact recovery and prognosis after gynecologic cancer surgery.

Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery