Actively Recruiting
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
Led by Dolunay ARIK · Updated on 2025-12-19
140
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia. PIH is defined as a drop in mean arterial pressure of ≥30% from baseline or below 65 mmHg within the first 20 minutes after anesthesia induction, prior to surgical stimulation. The primary objective is to determine the frequency of PIH in elderly oncology patients. Secondary objectives include evaluating the association of PIH with age, ASA score, cancer type, oncological treatments (chemotherapy/radiotherapy), comorbidities, medication use, anemia, biochemical parameters, and preoperative perfusion index (PI) and pleth variability index (PVI). Findings from this study are expected to contribute to improved perioperative management and to the development of tailored anesthesia protocols for geriatric oncology patients.
CONDITIONS
Official Title
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 65 years of age or older
- Diagnosis of cancer and scheduled for surgery
- Ability and willingness to provide written informed consent
- ASA physical status class II-IV
You will not qualify if you...
- Under 65 years of age
- No confirmed cancer diagnosis
- Refusal to provide written informed consent
- Undergoing regional anesthesia
- Presence of tracheostomy or multiple intubation attempts
- History of peripheral arterial disease
- Use of vasopressors before surgery
- Uncontrolled hypertension (blood pressure >180/110 mmHg)
- Advanced heart failure (ejection fraction <40%)
- Severe arrhythmias preventing reliable hemodynamic monitoring
AI-Screening
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Trial Site Locations
Total: 1 location
1
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
Ankara, Ankara, Turkey (Türkiye), 06200
Actively Recruiting
Research Team
D
Dolunay arık
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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