Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04493996

Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

Led by Heart and Brain Research Group, Germany · Updated on 2026-02-17

100

Participants Needed

1

Research Sites

289 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Postoperative delirium (POD) and postoperative cognitive decline (POCD) can be observed after cardiosurgical interventions. Taken together, these postoperative neurocognitive dysfunctions contribute to increased morbidity and mortality and higher economic costs. Preoperative risk factors of postoperative neurocognitive dysfunctions, such as decreased neuropsychometric performance or decreased cognitive daily activities, can be interpreted as reduced cognitive reserve. The aim of this study is to build up cognitive reserves to protect against the development of POD and POCD through preoperative, home-based, cognitive training.

CONDITIONS

Official Title

Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled for elective cardiac surgery such as coronary artery bypass, aortic or mitral valve replacement/reconstruction, or combination surgery with standardized extracorporeal circulation
  • Sufficient knowledge of German to complete cognitive training and tests
Not Eligible

You will not qualify if you...

  • History of stroke
  • Preexisting psychiatric or neurological disorders that may impair neuropsychological performance

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Cardiac Surgery, Kerckhoff-Klinik GmbH

Bad Nauheim, Germany, 61231

Actively Recruiting

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Research Team

M

Marius Butz, Dipl.-Psych.

CONTACT

M

Martin Jünemann, Dr.med,M.Sc.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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