Actively Recruiting
Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis
Led by Emory University · Updated on 2025-07-16
138
Participants Needed
1
Research Sites
97 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
N
National Multiple Sclerosis Society
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.
CONDITIONS
Official Title
Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per The 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS, or a healthy volunteer without a diagnosis of multiple sclerosis or any related neurological conditions
- Fluent in speaking and understanding English
- Subjects with multiple sclerosis have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months
You will not qualify if you...
- Clinically isolated syndrome or radiologically isolated syndrome
- Worsening MS symptoms during the prior 60 days
- Immunotherapy change in the prior 60 days
- Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
- Systolic blood pressure > 180 mmHg and/or diastolic blood pressure > 90 mmHg at rest
- Static visual acuity with correction of worse than 1.0 logMAR
- Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus)
- Convergence insufficiency
- Intra-nuclear ophthalmoplegia
- Vestibular Migraine
- Major orthopedic conditions that limit cervical spine range of motion or that alter walking
- Self-reported current or potential for pregnancy during enrollment
- Ongoing participation in vestibular rehabilitation for dizziness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Emory Univeristy
Atlanta, Georgia, United States, 30329
Actively Recruiting
Research Team
C
Colin Grove, PT, DPT, MS, PhD
CONTACT
C
Colin Grove
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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