Study of Factors Influencing Portal Vein Thrombosis Recovery in Adults with Cirrhosis and Gastroesophageal Varices

What this Trial Is About

Researchers are studying portal vein thrombosis PVT in patients who have cirrhosis and gastroesophageal varices GEV. This observational study, conducted at Zhongshan Hospital of Fudan University, aims to provide new insights into how PVT is diagnosed, monitored, and factors that affect its recanalization. The goal is to improve understanding for patients, families, and healthcare providers regarding this disease and its clinical management. The study observes patients who have been diagnosed with cirrhosis, confirmed gastroesophageal varices by endoscopy, and PVT confirmed by CTA imaging at admission. There are no interventions or treatments assigned by the study, as it is observational and retrospective-prospective in design. Researchers review patient records and imaging results over time to assess PVT recanalization and related outcomes. Participants are followed with abdominal imaging assessments starting from admission to track PVT recanalization at 1 year and 5 years, as well as occurrences of death or non-improved PVT. The main outcome measured is PVT recanalization within 1 year. Secondary outcomes include survival rates and PVT progression over 5 years. This long-term follow-up allows researchers to understand the disease course and factors influencing treatment outcomes.

Indicators Affecting PVT Recanalization